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The chemotropic factor semaphorin 3A has been shown to act in both the axonal and dendritic guidance of cortical pyramidal neurons.
Early response genes encoding potential regulators of pathogen and wound-induced plant responses have been identified using gene expression profiling.
The existence of several distinct plant signaling pathways regulating changes in gene expression in response to wounding has been demonstrated using cDNA microarray analysis.
MOLMOL is a molecular graphics program designed for display and analysis of biological macromolecules, particularly protein or DNA structures determined by nuclear magnetic resonance spectroscopy.
XREFdb is part of an attempt to identify connections between the genetics of model organisms and mammalian phenotypes.
Since its inception in 1996, Pfam has aimed to be a comprehensive database of protein families defined by the presence of shared domains.
A homolog of the tumor suppressor p53 causes damage-induced apoptosis in fruit flies.
A homolog of the tumor suppressor p53 regulates apoptosis in fruit flies.
Specific DNA targets of chromatin-associated factors have been enzymatically marked in order to identify loci that are regulated at the level of chromatin organization in eukaryotes.
Small RNAs involved in rRNA methylation and ribosome biogenesis have been found in Archaea.
Large quantities of biologically active human somatotropin have been successfully produced in plants, highlighting the promise of plant biotechnology for producing pharmaceuticals.
Systematic analysis of the chloroplast and its photosynthetic machinery has begun, using a combination of two-dimensional gels, mass spectroscopy, protein sequencing and genome databases.
A portion of the rice genome has been examined in order to evaluate the feasibility of using rice as a surrogate genome for map-based cloning of maize genes.
A comprehensive analysis has identified and localized all yeast nucleoporins in nuclear pore complexes.
A report from the Genome Biology session of the 4th annual conference on microbial genomes, Virginia, February 12-15, 2000.
A report from the Keystone Protein kinase C: structure, regulation and cellular function meeting, New Mexico, February 5-10, 2000.
Proteins of the Rab and SNARE families target vesicles to their intracellular destinations. A comparison of these families from the budding yeast, fission yeast, nematode and fruitfly genomes has implications ...
Genomic sequencing of the Toll-like receptor 4 gene in humans, mice, chimpanzee and baboon has shown that the Tlr4 protein is polymorphic.
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