Fig. 5
From: The gene regulatory mechanisms shaping the heterogeneity of venom production in the Cape coral snake
Transcription factor binding sites in promoter of 3 FTx genes. A Alignment and conservation of promoter sequences of 3 FTx with the TFBSs identified based on the toxin cells. The gray regions represent alignment gaps. The cytotoxins are highlighted in bold (i.e., 3 FTx-24, 3 FTx-25, and 3 FTx-26). B Co-evolution of peptide and promoter sequence of 3 FTX (see Additional file 1: Figs. S15 and S16 for bootstrap values; Additional file 1: Fig. S17 for correlation of patristic values). The phylogenetic trees inferred from both promoter and peptide sequences reveal similar evolutionary histories for both regions. The cytotoxins and their relationships are highlighted in bold