Fig. 6
From: Parent-of-origin regulation by maternal auts2 shapes neurodevelopment and behavior in fish
Evolutionarilyconserved oocyte genes linked to behavior and nervous system development. a Venn diagram displaying zebrafish and mouse oocyte genes associated with either behavior or nervous system development (NSD). The green area corresponds to genes expressed in oocytes of both species that are associated with both GO terms. b Boxplots (left panel) show the distribution of the disease pleiotropy index (DPI) of human gene orthologs to all common zebrafish and mice oocyte genes (grey), genes associated with behavior GO term (blue), NSD GO term (yellow), or both GO terms (green). The number of genes is indicated for each category. For each group of genes, bar plots (right panel) show the proportion of genes in each DPI class. Within each group of genes, differences between DPI classes were assessed using chi square tests. Groups sharing the same letter are not significantly different (P < 0.05). c DPI of human orthologs of evolutionarily conserved oocyte genes associated with behavior and neurodevelopment (N = 92). Symbols of genes with DPI above 0.75 are displayed