Fig. 3
From: Peak analysis of cell-free RNA finds recurrently protected narrow regions with clinical potential
CfPeak sensitively finds peaks in the public and artificial datasets. A Peak number, abundance (CPM), and fold change of adjacent peak depth of four methods (consensus peak). B Recall, precision, and F1 score of four methods using plasma-benchmark. C Recall, precision, and F1 score of four methods using general-benchmark. D Example regions with peaks were variably detected by four methods. Y axis: min–max scaled depth. X axis: transcriptomic coordinates in full-length transcript. Alternative transcripts were plotted below if exist. E Illustration of artificial data generation. F Recall of four methods in artificial plasma samples with different minor-origin fraction. Tx, transcripts; FC, fold change