Fig. 1
From: Peak analysis of cell-free RNA finds recurrently protected narrow regions with clinical potential
Narrow peaks can be recurrently detected in small cfRNA-seq data. A Four example regions with recurrent peaks. X axis and Y axis of each region stand for transcriptomic coordinate relative to full-length transcript and min–max scaled read depth. Two random samples/tracks were plotted for each dataset. B–E Comparison of representative datasets (GSE50676, GSE148861, and GSE71008) from three different data types. B Ridge plot showed read clusters’ distribution around peak regions. X axis stands for extended 50 nt from scaled peak regions. Top: Y axis means scaled read depth. Bottom: Y axis of heatmap means regions ranked by mean of scaled depth each data type, color intensity means scaled count signal. C Ridge plot showed peak length distribution. D Ridge plot showed peak abundance distribution. E Stacked bar plot showed ratio of different peak precursor (transcript) species. NEB, NEBnext small RNA-seq Kit; TGIRT, thermostable group II intron reverse transcriptases