Table 5 High impact novel unique Meishan variants associated with phenotypic differences related to obesity and cardiovascular disease
From: Development of a whole-exome sequencing kit to facilitate porcine biomedical research
Breed | Gene | Mutation type | Amino acid length of gene | Normal gene function |
|---|---|---|---|---|
Meishan | ABCC9 | c.116 delT p.Val39fs | 1603 | Regulatory subunit of a cardiac ATP-sensitive potassium channel |
Meishan | ACOT4 | p.Ser6* | 464 | Hydrolyze fatty acyl-CoAs into fatty acids and CoA in peroxisomes and mitochondria |
Meishan | PL1 N1 | p.Ser494* | 578 | Mobilization of fats in adipose tissue |
Meishan | GRB10 | p.Lys534* | 548 | Growth factor |