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Fig. 3 | Genome Biology

Fig. 3

From: Long-read sequencing reveals novel isoform-specific eQTLs and regulatory mechanisms of isoform expression in human B cells

Fig. 3

Effects of ieQTLs. A Distribution of gene eQTL-specific (green), common (brown), and ieQTL-specific (yellow) variants relative to the gene body. Gene size was adjusted to 25,000 bp, which is the average gene size. TSS, transcription start site; TES, transcription end site. eQTL with number of linked variants < 30 were used for the graph. B Comparison of amino acid sequences and functional motifs between major isoforms and minor isoforms affected by ieQTLs. C Number of GWAS hits found in gene eQTL-specific (green, n = 10), common (brown, n = 120), and ieQTL-specific (yellow, n = 242) variants. Red bars indicate hematological or blood-related traits in the GWAS hits

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Genome Biology

ISSN: 1474-760X

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