Table 1 Comparison of ESCOTT with EVE (ensemble), ESM1b and AlphaMissense on human proteins in the ProteinGym dataset. Average Spearman correlation coefficients are reported for all, single and multiple mutation experiments on the 32 human proteins in the ProteinGym dataset. “Average” refers to Spearman correlation computed on the average vector associated to a matrix. For each subset, the best result is in bold and the second best is in italic

From: PRESCOTT: a population aware, epistatic, and structural model accurately predicts missense effects