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Fig. 2 | Genome Biology

Fig. 2

From: Variant effect predictor correlation with functional assays is reflective of clinical classification performance

Fig. 2

The top 30 out of 97 tested VEPs ranked based on performance against the DMS benchmark. VEPs are ranked according to their average win rate against all other VEPs in pairwise Spearman’s correlation comparisons across all DMS datasets. The number of proteins for which each VEP had scores included is indicated in the right column of the plot. Those indicated with * had some DMS datasets excluded to avoid circularity concerns. Error bars represent the standard deviation in the rank score across 1000 bootstrap permutations of the benchmarking DMS datasets. The full ranking of all VEPs and all pairwise win rates are available in Additional file 2: Table S3

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Genome Biology

ISSN: 1474-760X

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