Fig. 6
From: Bayesian multi-study non-negative matrix factorization for mutational signatures
A Distribution of total numbers of mutations per sample in each of the four groups considered in the breast cancer application. B (Top) Signature indicator matrix estimated using the recovery-discovery model. Signatures in the discovery component are labeled beginning with “D.” (Bottom) As above, but showing the proportion of samples in each study with more than 5% of total exposures attributed to each signature. C (Left) Signature D1 from the discovery component found to belong to both PCAWG 30–39 and PCAWG 55+, compared to (right) SBS5 from COSMIC v3.2