Fig. 4

Editing plasticity is associated with gene evolvability. A Distribution of editing plasticity of all genes in B73 reference genome. Some important genes are highlighted. B Tissue-specific expression pattern for two types of genes with extreme EP values. Tau values of the genes are shown to measure the tissue specificity of expression. C The evolvability space of Zea mays. Evolvability vectors for the 3-Kbp regulatory sequences of each gene are projected onto the evolvability space. Expression change patterns (colored curve) of three archetypes are demonstrated. D Expression patterns of three groups in the evolvability space. The maximum TPM values (left panel) and the natural expression fluctuation across 255 maize inbred lines for three groups (middle panel) are demonstrated. EP values of genes in three groups (right panel) are shown. Student’s t test P values are presented. *P < 0.05, **P < 0.01, ***P < 0.001. E Landscape of editing plasticity in the evolvability space. Evolvability vectors (points) are projected onto the evolvability space and are colored by editing plasticity