Fig. 3

The performance of stDyer on the DLPFC dataset by jointly considering multiple slices. a The spatial organization of four slices in a section. b Visualization of spatial domains on slice 151510 and ARI scores for the five methods described in a and stDyer on the single slice (stDyer(S), slice 151510). stDyer(M): stDyer on four slices (101507, 151508, 151509, 151510). c Comparison of five methods that support spatial domain clustering on multiple slices. The p-values were computed by the Wilcoxon rank-sum test (****: p-value < 0.0001; **: p-value < 0.01; *: p-value < 0.05). d UMAP visualization for the four slices (151507, 151508, 151509, and 151510) by labeling units with the annotated spatial domains and predicted spatial domains