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Table 3 Overview of performances of each methodology across three different datasets collecting reference SL pairs

From: PRODE recovers essential and context-essential genes through neighborhood-informed scores

 

ROC AUC

PR AUC

Diff. GE

PRODE

NSUM

NMAX

RWR

Np-value

Diff. GE

PRODE

NSUM

NMAX

RWR

Np-value

Iso. screen

0.58

0.68

0.59

0.55

0.57

0.55

0.72

0.80

0.72

0.71

0.71

0.67

Double KO

0.57

0.66

0.57

0.56

0.57

0.54

0.72

0.78

0.70

0.70

0.71

0.69

SL db

0.63

0.71

0.63

0.61

0.62

0.54

0.73

0.80

0.73

0.70

0.72

0.64

  1. Diff. GE is differential gene effects; MUFS is MUFFINN sum; MUFM is MUFFINN max; RWR is random walk with restart.
  2. Highlighted in bold are PRODE's performances
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Genome Biology

ISSN: 1474-760X

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