Fig. 4
From: Multi-omics analysis in primary T cells elucidates mechanisms behind disease-associated genetic loci
Gene regulatory mechanisms underlying the rs968567 locus. A Chromatin accessibility of peak chr11:61,816,418 vs the genotype of rs968567. B Chromatin accessibility of peak chr11:61,827,746 vs the genotype of rs968567. C Chromatin accessibility of peak chr11:61,834,520 vs the genotype of rs968567. D Chromatin accessibility of peak chr11:61,871,089 vs the genotype of rs968567. E Visualization of the region surrounding rs968567. Top: ATAC-seq peaks. The intensity of the color indicates the average peak height of the peak, whilst position across the Y-axis indicates Pearson’s correlation with the genotype of rs968567. Middle: Genes from Gencode v29. The red dots indicate the transcription start sites. Bottom left: Correlation between the Hi-C contacts and the genotype of rs968567. Bottom right: Merged Hi-C map. F Expression of FADS1 with the genotype of rs968567. G Expression of FADS2 with the genotype of rs968567