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Table 1 Top enriched Biological Process GO terms from the INTACT-GSE gene set enrichment analysis

From: Multi-INTACT: integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits

Biological Process GO term ID

Term

INTACT-GSE enrichment estimate (log odds ratio)

95% confidence interval

GO:0008203

Cholesterol metabolic process

3.069

(1.907, 4.231)

GO:0008202

Steroid metabolic process

2.633

(1.609, 3.657)

GO:0006644

Phospholipid metabolic process

2.141

(1.057, 3.225)

GO:0006629

Lipid metabolic process

2.026

(1.045, 3.007)

GO:0042632

Cholesterol homeostasis

2.018

(0.840, 3.197)

GO:0006631

Fatty acid metabolic process

1.997

(0.931, 3.064)

GO:0006082

Organic acid metabolic process

1.978

(1.025, 2.930)

GO:0016042

Lipid catabolic process

1.913

(0.854, 2.972)

GO:0055088

Lipid homeostasis

1.894

(0.737, 3.051)

GO:0046395

Carboxylic acid catabolic process

1.893

(0.842, 2.943)

GO:0009636

Response to toxic substance

1.852

(0.715, 2.989)

GO:0006805

Xenobiotic metabolic process

1.805

(0.520, 3.091)

GO:0001889

Liver development

1.616

(0.333, 2.899)

GO:0007041

Lysosomal transport

1.616

(0.333, 2.899)

GO:0007034

Vacuolar transport

1.485

(0.223, 2.747)

GO:0042594

Response to starvation

1.373

(0.124, 2.621)

  1. Each listed term is nominally significant at the 5% level