Fig. 7

Overlap between gene-metabolite pairs discovered by integrative approaches and the knowledge-based approach (KBA). a INTACT using GTEx multi-tissue eQTL data. Numbers represent pairs implicated in at least one tissue. b INTACT using the UK Biobank pQTL data set. c Multi-INTACT using both GTEx and UK Biobank QTL data sets. There are 289 unique pairs implicated by KBA and either INTACT-expression or INTACT-protein. Of these pairs, 287 are represented in the intersection of the KBA and Multi-INTACT discoveries