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Fig. 8 | Genome Biology

Fig. 8

From: Engineering a bacterial toxin deaminase from the DYW-family into a novel cytosine base editor for plants and mammalian cells

Fig. 8

Identifying structurally related proteins of SsdAtox using Foldseek. a Workflow of the SsdAtox structure search based on Foldseek and filtering for conserved motifs. b Phylogenetic clustering of the top 50 highest-scored candidates and six manually selected candidates from plants. Eighteen candidates labelled in red contain the conserved motifs from SsdAtox. c Sequence alignment of the 18 candidates to SsdAtox, with conserved motifs shown above the alignment. Amino acid G103 from SsdAtox is indicated by an asterisk

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Genome Biology

ISSN: 1474-760X

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