Fig. 1

Dataset of Streptomyces genomes and BGC statistics. A Number of Streptomyces genomes from the NCBI RefSeq database as of 30 June 2023. The final bar includes newly sequenced high-quality genomes from our recent study [22]. Genomes are categorized by assembly quality: HQ (high-quality), MQ (medium-quality), and LQ (low-quality). B Scatter plot illustrating the relationship between genome length and the number of BGCs in 2371 genomes of the MQ and HQ categories. Annotations represent information on selected strains. C Breakdown of the common types of BGCs detected in the HQ and MQ genomes. Color-coded bars highlight BGC similarity percentages against the MIBiG database: gray for < 50%, light green for 50–80%, and green for > 80%. Bar annotations represent a tally of MIBiG entries with > 80% similarity for the detected BGCs. Abbreviation of BGC types: T1PKS, type 1 polyketide synthase; T2PKS, type 2 polyketide synthase; T3PKS, type 3 polyketide synthase; Other PKS, hybrid BGCs with at least one PKS category BGC; NRPS, non-ribosomal peptide synthetase; NAPAA, non-alpha poly-amino acids like ε-polylysine; NI-siderophore, NRPS-independent siderophores; Other NRPS, hybrid BGCs with at least one NRPS category BGC; NRPS.T1PKS, hybrid BGC with one of NRPS and T1PKS BGCs; Other NRPS.PKS hybrids, hybrid BGC with PKS, NRPS, and other BGCs; RiPP, ribosomally synthesized and post-translationally modified peptide; Other RiPP, hybrid BGCs with one RiPP BGC; All other types, BGCs of other types than above