Table 2 Optimized parameters of CCLE simulations for different genomic regions in interphase S. pombe, meiotic S. cerevisiae, and mitotic S. cerevisiae
| Â | LEF density, \(\varvec{\rho }\) (1/kb) | Mean processivity, L (kb) | Persistence length (nm) | Cohesive cohesin density, \(\varvec{\rho }_{\varvec{c}}\) (1/kb) | Gaussian \(\varvec{\sigma }\) (kb) |
|---|---|---|---|---|---|
S. pombe | |||||
Chr1: 0.5–1.7 Mb | 0.033 (± 0.001) | 30.0 (± 0.7) | 85 (± 19) | 0.037 (± 0.003) |  |
Chr1: 4.2–5.4 Mb | 0.033 (± 0.001) | 31.2 (± 0.8) | 75 (± 23) | 0.014 (± 0.003) |  |
Chr2: 0.2–1.4 Mb | 0.033 (± 0.001) | 30.0 (± 0.8) | 80 (± 21) | 0.050 (± 0.004) |  |
Chr2: 1.8–3.0 Mb | 0.033 (± 0.001) | 30.0 (± 0.6) | 80 (± 13) | 0.028 (± 0.005) |  |
Chr3: 1.2–2.4 Mb | 0.030 (± 0.001) | 33.3 (± 1.0) | 95 (± 17) | 0.043 (± 0.004) |  |
S. cerevisiae | |||||
Chr13: 240–840 kb (meiotic) | 0.058 (± 0.003) | 38.4 (± 3.3) | 160 (± 19) | 0.018 (± 0.009) | 90 (± 25) |
Chr10: 100–700 kb (mitotic) | 0.033 (± 0.003) | 7.2 (± 0.2) | 60 (± 2) | 0 | 98 (± 3) |