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Fig. 2 | Genome Biology

Fig. 2

From: A comprehensive study of genetic regulation and disease associations of plasma circulatory microRNAs using population-level data

Fig. 2

a Manhattan plot showing the identified miR-eQTLs. The strongest association for each of 63 miRNAs reaching P < 2.4 × 10−11 is colour-labelled (yellow for cis, and green for trans). Highly pleiotropic loci were identified in locus chr14:100,655,022–101244293, the majority of which were cis-miR-eQTLs and in chr9:136,128,546–13,629,653, the majority of which were trans-miR-eQTLs. This plot only shows associations with P < 1.0 × 10−5. b Functional consequences of the identified miR-eQTLs on nearby and far genes. c Twenty miRNAs with the highest SNP-based heritability estimates

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Genome Biology

ISSN: 1474-760X

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