Fig. 4

CCCs analysis of Deng dataset. A Circos plot of CCCs among four cell types. B The number of CCCs is summarized by counting the number of significant L-R pairs in the form of a heatmap. C The heatmap illustrates the relative importance of mesenchymal cells based on significant CCCs from mesenchymal cells to other cell types. D The visualization highlights the important CCCs between mesenchymal cells and other cell types with a circos plot. E Sankey plot of CCC pathways of significant L-R-TF. F Ridge plot of significant TFs and their corresponding \({\text{TF}}_{{{\text{activity}}}}\) score. G Pathway enrichment analysis of differentially expressed genes regulated by TFs