Fig. 5

Application of VirRep to 128 real human gut metagenomes from 74 colorectal cancer patients and 54 healthy controls. a The number of viral populations of each category (x-axis) obtained by each method (y-axis). The maximum value in each column is highlighted in bold red font. b The significance (log10 transformed q-values) of viral populations (VPs) is given by the bar height. Horizontal line shows FDR at the level of 0.05. VPs with P < 0.001 and q < 0.05 are colored in dark gray, while others are colored in light gray. Shown are the top 90 significant VPs. c The average accuracy of tenfold cross-validation (repeated 10 times) of the logistic regression models versus the size of the marker set for each method. d Genome maps for viruses VP1279 and VP2811. e The phylogenetic tree of viruses VP1279 and VP2811