Fig. 4

General combination scheme of the Roary and ILP results. The left-hand side describes a trivial case, showing a Roary cluster with five genes that is also a RIBAP group. The middle panel shows two Roary clusters (three and two genes, respectively) that are finally merged into one RIBAP group with the help of the ILPs. The right-hand panel shows again two Roary clusters that result in two RIBAP groups. The smaller RIBAP group is labeled as a subgroup of the larger RIBAP group. A The original Roary clusters as determined at a sequence similarity threshold of 95%. B Extracted genes and their pairwise ILP connections. C The resulting RIBAP groups (and the original Roary clusters) after our merging procedure