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Fig. 4 | Genome Biology

Fig. 4

From: Detecting haplotype-specific transcript variation in long reads with FLAIR2

Fig. 4

Long-range features of inosines observed with nanopore sequencing. Aligned reads displaying a type II hyperediting, b coordinated editing, and c and d disruption of splicing in the presence of editing. In a and c, the top coverage tracks and reads are displaying the nanopore CTRL/ADAR KD samples, and the bottom three coverage tracks are Illumina CTRL KD samples. In b and d, the dataset on top displays the control nanopore reads and the bottom panel displays the ADAR knockdown reads. In b, orange marks correspond to A → G mismatches and in a, c, and d, positions marked with blue mismatches are T → C mismatches (A → G on the negative strand)

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