Fig. 4

Highly nested SVs found in the SKBR3 breast cancer cell line by Leaf-cuteSV. Images are generated by Integrative Genomics Viewer (IGV). Sequences of different strands are highlighted with different colors. The nested SV in the first subfigure comprises two deletions of 1441 bps and 750 bps on the two sides and one 976-bps duplication in darker red embedded in the inversion. The nested SV in the second subfigure comprises two deletions and one 987-bps insertion highlighted by rectangles embedded in the inversion