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Fig. 6 | Genome Biology

Fig. 6

From: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells

Fig. 6

Amplicon sequencing confirms no indel formation at base-edited sites when combining Cas12a nuclease and Cas9 BE. Summary of CRIPResso2 analysis showing the frequency of total modified reads, frequency of indels, and quantification of intended base editing-mediated base changes mapped to B2M (a) or to CIITA (b). n = 5 healthy donors

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Genome Biology

ISSN: 1474-760X

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