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Fig. 4 | Genome Biology

Fig. 4

From: Personalized genome assembly for accurate cancer somatic mutation discovery using tumor-normal paired reference samples

Fig. 4

Improvements of Illumina short-read and PacBio long-read mappings with personalized genome HCC1395BL_v1.0 reference as compared to GRCh38. A Percentages of properly paired reads in alignments for tumor and normal samples. B Reductions of non-properly paired reads in alignments for tumor and normal samples with personalized genome HCC1395BL_v1.0 as compared to GRCh38. C Reductions of mismatches in alignments for tumor and normal samples with personalized genome HCC1395BL_v1.0 as compared to GRCh38. D Reductions of split reads in alignments for tumor and normal samples with personalized genome HCC1395BL_v1.0 as compared to GRCh38. E Standard deviations of read coverages in short-read alignments with personalized genome HCC1395BL_v1.0 as compared to GRCh38. F Standard deviations of read coverages in PacBio long-read alignments with personalized genome HCC1395BL_v1.0 as compared to GRCh38

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Genome Biology

ISSN: 1474-760X

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