Fig. 2
From: Blood-based epigenome-wide analyses of cognitive abilities
Measured and epigenetic cognitive ability associate with brain structure and show regional overlap with cortical loci. Cognitive ability measures with global brain imaging associations in LBC1936 with 95% confidence intervals; measured g (turquoise triangle), Epigenetic Score (EpiScore; orange circle) (A). Results of cortical volume at age 73 years regressed against cognitive g EpiScore (orange), measured g (turquoise) and the spatial extent of overlap (pink) in cortical loci. Colours, representing q values, are superimposed on an average surface template. A false discovery rate threshold of 0.05 is used to control for multiple comparisons; results are corrected for sex, age in days at brain scanning and intracranial volume (n=551) (B)