Fig. 2

The average performance (а, b AUC ROC; c Pearson correlation coefficient) achieved by PWMs (rows) on particular data sets (columns). The average is taken over all binding motifs for TFs from the same family of DNA recognition domains according to the CIS-BP TF family classification and for all experiments for all TFs from the family of their DNA recognition domains. The PWMs were benchmarked on ChIP-seq (a), HT-SELEX 10% (b), and PBM (c) data. Only families with no less than 2 PWMs, 2 ChIP-seq, and 2 SELEX data sets are shown